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At any one time, roughly a quarter of the women between 12 and 50 years of age are likely to be in the paramenstrual week of their cycle, defined as four days before and four days after the first day of flow.However, women in the paramenstruum are vastly overrepresented among women involved in car accidents (48 percent), newly admitted women prisoners (49 percent), emergency hospital admissions (53 percent) and attempted suicides (more than 50 percent).It was sanctioned behavior, based on a belief central to his culture: Any contact a man had with menstrual blood -or even with a menstruating woman - would, as one anthropologist put it, ''corrupt his vital juices, permanently dull his wits and eventually lead to slow death.'' The world has come a long way from such excess, but that is not to say the journey is complete.The vagaries of present-day attitudes toward menstruation can be charted by the shifting definition of menstrual distress.

Roughly one-half of American women are said to experience menstrual distress to some minor degree.Menstruation as we know it today is largely a product of contraception and of an increase in the number of childbearing years.Until this century, most women spent the years between their first menses, around the age of 14, to their menopause, at age 35 or 40, either pregnant or breast-feeding.When the level of the hormone estrogen gets too low, a signal is sent from the hypothalamus to the nearby pituitary gland, which releases a hormone to the ovary.This stimulates the development of about 20 of the ovary's hundreds of thousands of immature eggs, known as follicles.

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